Reduction in lesions from Lmax : a new concept for assessing efficacy
نویسندگان
چکیده
1 Department of Dermatology, Charité – University Medical Centre Berlin, Charité Platz 1, Berlin, D-10117, Germany 2 Department of Dermatology, Monklands Hospital, Airdrie, Lanarkshire, ML6 0JS, UK 3 Department of Dermatology, University of L’Aquila, Via Vetoio Coppito 2, 67100 L’Aquila, Italy 4 Service de Dermatologie Allergologie, Hôpital Cochin, 89 rue d’Assas, 75006 Paris, France and Université Paris 5 Descartes, Paris, France 5 Meda Pharma GmbH & Co. KG, Benzstrasse 1, 61353 Bad Homburg, Germany 6 Department of Dermatology, Institut Universitari Dexeus, Av. Carles III 71-75, 8
منابع مشابه
Reduction in lesions from Lmax: a new concept for assessing efficacy of field-directed therapy for actinic keratosis. Results with imiquimod 3.75%.
BACKGROUND Current parameters for assessing the efficacy of actinic keratosis (AK) treatments compare clinical lesions at the start and end of a study. However, the sun-exposed field also contains subclinical lesions which may become detectable during treatment. Lmax, the maximum lesion count during treatment, is a new concept to better assess the efficacy of field-directed AK therapies. Measur...
متن کاملLong-term sustained lesion clearance from Lmax with imiquimod 3.75%, a new field-directed treatment for actinic keratosis.
BACKGROUND In patients with actinic keratosis (AK), subclinical and clinical lesions coexist across large areas of sun-exposed skin. The long-term efficacy of AK treatments depends on their ability to eradicate both types of lesions across the entire field. OBJECTIVE To assess the long-term efficacy of imiquimod 3.75% using the reduction in lesions from Lmax (maximum lesion count during treat...
متن کاملReduction in lesions from Lmax : a new concept for assessing efficacy of field - directed therapy for actinic
1 Department of Dermatology, Charité – University Medical Centre Berlin, Charité Platz 1, Berlin, D-10117, Germany 2 Department of Dermatology, Monklands Hospital, Airdrie, Lanarkshire, ML6 0JS, UK 3 Department of Dermatology, University of L’Aquila, Via Vetoio Coppito 2, 67100 L’Aquila, Italy 4 Service de Dermatologie Allergologie, Hôpital Cochin, 89 rue d’Assas, 75006 Paris, France and Univer...
متن کاملEfficacy of EMLA cream in reduction of the pain of intralesional Corticosteroid injection in Alopecia Areata
Background: EMLA cream is a eutectic mixture of Lidocaine and Prilocaine used to induce local anesthesia for dermatological procedures. Objective: This study was designed to evaluate the efficacy of EMLA cream in reducing the pain of intralesional injection of steroid in patients with alopecia areata. Patients and Methods: This study was carried out on 27 alopecia areata patients. The injection...
متن کاملEfficacy and tolerability of adapalene 0.1%-benzoyl peroxide 2.5% combination gel in treatment of acne vulgaris in Indian patients: A randomized investigator-blind controlled trial
Background: Topical retinoid based combinations are recommended to enhance the outcome of acne treatment. Adapalene-benzoyl peroxide (BPO) combination gel was approved in 2009 for acne treatment. The aim of this study was to evaluate the efficacy and tolerability of adapalene 0.1%-benzoyl peroxide 2.5% combination gel compared to adapalene 0.1% gel monotherapy and benzoyl peroxide 2.5% gel mono...
متن کامل